What medical breakthroughs and new technologies will make this possible? In this brilliantly wide-ranging, one-stop guide WIRED journalist James Temperton outlines the medical revolutions that are transforming healthcare.

Ron Williamson was a star college sportsman in the small town of Ada, Oklahoma. When he left to pursue his dreams he seemed destined for glory. But years of injury, drinking, drugs and women took their toll, and he returned to Ada a lonely drifter. Soon after his homecoming, a local cocktail waitress was raped and murdered.

John Gimlette's travels through the eastern extreme of the Americas, which mirrors that of Dr Eliot Curwen, his great-grandfather, who spent a summer there as a doctor in 1893. Using Curwen's journal, John Gimlette revisits the places his great-grandfather encountered, and along the way explores his own links with this land.